A few of the synthesized compounds in synthetic cannabinoids bind much more strongly to THC receptors than normal marijuana, which may lead to more potent, unpredictable or risky consequences.
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Experiments have strongly linked unique synthetic cannabinoids with psychosis.[82][eighty three][eighty four][eighty five] The use of synthetic cannabinoids could be affiliated with psychosis and physicians are commencing to analyze if some individuals with inexplicable psychotic signs or symptoms might have at one particular level utilized synthetic cannabinoids. In distinction to most other leisure prescription drugs, the spectacular psychotic state induced by usage of synthetic cannabinoids has long been reported, in various instances, to persist for many months, and in one situation for seven months, right after full cessation of drug use.
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